I am an Associate Professor and Chief Scientist at JancsiTech, where I lead the AI medical imaging R&D team. Previously, I was the Research Lead at ByteDance AI Healthcare Department and a Postdoctoral Research Fellow at Stanford University, working with Prof. Lei Xing.
My research focuses on medical AI, including medical image reconstruction (CT/MRI), cancer prediction, and image analysis. I have published 85+ papers in top venues including Nature Communications, Lancet Digital Health, IEEE TMI, and MIA, with 2300+ citations.
News
[2025] One paper on Uncertainty-aware CT Metal Artifact Reduction published on arXiv
[2025] One paper on SSA3D: Dental Abutment Design published on arXiv
[2024] One paper on Reliable Deep Diffusion Tensor Estimation published on arXiv
[2023] One book chapter on Metal Artifact Reduction published in Medical Image Synthesis book
[2022] One paper on Control Volume Mapping published in Computers in Biology and Medicine
[2022] One paper on Retinal Photoreceptor Quantification published in Frontiers in Neuroscience
[2021] One paper on ComputeCOVID19+ accepted by ACM ICMIP
[2021] One paper on Human-Computer Interaction published in Wireless Communications and Mobile Computing
[2019] One paper on Matlab Toolbox for Feature Ranking accepted by ICMIPE
[2019] One paper on Multi-material Identification in Photon Counting CT published in Medical Imaging
[2018] One paper on Activation Functions for Image Sharpness Assessment published in SPIE
[2026] One paper accepted by Applied Soft Computing (Brain Tumor Segmentation)
[2025] 🔥 ELSEVIER & Stanford Top 2% Scientists in the World 2025
[2025] 🔥 One paper accepted by Nature Communications (DL for colorectal lesion classification)
[2025] One paper accepted by MICCAI 2025 (Medical Image Synthesis)
[2025] One paper accepted by IJCAI 2025 (EEG generation)
[2024] 🔥 One paper accepted by Medical Image Analysis (CBCT-to-CT Synthesis)
[2024] One paper accepted by JITC (Pathomics-driven immunotherapy response)
[2024] One paper accepted by JCI (Immune context assessment)
[2024] One paper accepted by IEEE JBHI (Diffusion Tensor Imaging)
[08/2023] Two papers accepted by ICASSP 2024.
[08/2023] One paper accepted by ACM MM 2023.
[08/2023] One paper accepted by Nature Communications.
[08/2023] Two papers accepted by MICCAI workshop (CMMCA2023).
[07/2023] One paper accepted by ACM MM 2023.
[03/2023] One paper accepted by ICLR 2023.
[09/2022] Acting as Program Committee member On DLBIBM 2022.
[09/2022] One paper accepted by TMI.
[06/2022] 1st place on the 2022 VizWiz Grand Challenge (CVPR2022).
[06/2022] One paper accepted by MICCAI.
[04/2022] One paper accepted by The Lancet Digital Health.
[08/2021] One paper about self-supervised CT super-resolution accepted by CBM.
[07/2021] One paper about metal artifact reduction in CT accepted by PMB.
[07/2021] One paper about Covid-19 accepted by ICPP2021.
[07/2021] One paper about Low-dose CT accepted by Medical Physics.
[07/2021] One paper about multi-organ segmentation accepted by Medical Image Analysis.
[05/2021] One paper about Low-dose CT accepted by MICCAI.
[04/2021] One paper about TOF-MRA accepted by Computers in Biology and Medicine.
[03/2021] Grant about Dual-energy CT approved by Stanford.
[02/2021] Grant about Low-count PET approved by Reflexion.
[02/2021] One paper accepted by Medical Physics.
[09/2020] One paper accepted by TMI.
[08/2020] Grant approved by NSFC.
[07/2020] "matFR: a matlab toolbox for feature ranking" accepted by Bioinformatics.
[06/2020] Two abstracts accepted by AAPM 2020.
[06/2019] One paper accepted by Medical Physics.
[04/2018] One paper about sparse-view CT reconstruction accepted by TMI.
[03/2019] One paper accepted by IEEE Access.
[06/2017] One paper about ring artifact removal in cone-beam CT accepted by PMB.
[10/2016] One paper about carbon nanotube based CT accepted by Physica Medica.
Research Interests
🧠 Medical AI
Deep learning for medical image analysis, reconstruction, and diagnosis
📡 CT/MRI Imaging
Low-dose CT, sparse-view reconstruction, metal artifact reduction
🎯 Cancer Prediction
Multi-task deep learning for cancer prognosis and immunotherapy response
🔬 Image Synthesis
Diffusion models for CBCT-to-CT synthesis, medical image translation
Y Zhang, J Wang, X Yang, X Zhang, A Abulizi, H Jiang, G Zhou, H Liao, ..., Z Zhang
"Advancing brain tumor segmentation in smart healthcare via T1-generated virtual multimodal MRI fusion."
Applied Soft Computing, 2026. [DOI]
YZ Zhang, JH Huang, J Wang, Z Li, Z Wang, G Zhou, Z Zhang, G Yu
"High-Fidelity Unified One-to-Many Medical Image Synthesis via Text-Conditioned Latent Diffusion."
MICCAI 2026, 2026. [DOI]
2025
J Wang, M Liu, H Liao, J Fan, H Zhu, T Ma, D Yang, F Ni, F Zhang, G Jin, ..., Z Zhang
"Development of deep learning-based narrow-band imaging endocytoscopic classification for predicting colorectal lesions."
Nature Communications, 2026. [DOI]
Y Zhang, L Li, J Wang, X Yang, H Zhou, J He, Y Xie, Y Jiang, W Sun, ..., Z Zhang
"Texture-preserving diffusion model for CBCT-to-CT synthesis." [GitHub]
Medical Image Analysis, 2025. [DOI]
L Li, J Liu, H Xiao, G Zhou, Q Liu, Z Zhang
"Expert guidance and partially-labeled data collaboration for multi-organ segmentation."
Neural Networks, 2025. [DOI]
Y Chen, J Li, Q Lu, Y Wu, X Liu, Y Gao, Y Feng, Z Zhang, X Zhang
"Spherical harmonics-based deep learning achieves generalized and accurate diffusion tensor imaging."
IEEE Journal of Biomedical and Health Informatics, 2025. [DOI]
E Zhang, Z Zhang, T Hanakawa
"Category-aware EEG image generation based on wavelet transform and contrast semantic loss."
IJCAI 2025, 2025. [DOI]
Y Chen, Y Guo, X Liu, Z Zhou, H Wu, ..., Z Zhang, et al.
"SSA3D: Text-Conditioned Assisted Self-Supervised Framework for Automatic Dental Abutment Design."
Medical Image Analysis, 2025. [arXiv]
2024
Z Han, Z Zhang, X Yang, Z Li, S Sang, MT Islam, AA Guo, Z Li, X Wang, ...
"Development and interpretation of a pathomics-driven ensemble model for predicting the response to immunotherapy in gastric cancer."
Journal for Immunotherapy of Cancer, 2024. [DOI]
Z Sun, T Zhang, MU Ahmad, Z Zhou, L Qiu, K Zhou, W Xiong, J Xie, ..., Z Zhang, ...
"Comprehensive assessment of immune context and immunotherapy response via noninvasive imaging in gastric cancer."
The Journal of Clinical Investigation, 2024. [DOI]
L Zhou, L Zhou, C Wu, Z Zhang
"Multitask connected U-Net: automatic lung cancer segmentation from CT images using PET knowledge guidance."
Frontiers in Artificial Intelligence, 2024. [DOI]
S Xun, M Jiang, P Huang, Y Sun, D Li, Y Luo, H Zhang, Z Zhang, X Liu, ...
"Chest CT-IQA: A multi-task model for chest CT image quality assessment and classification."
Displays, 2024. [DOI]
L Li, J He, Y Tang, Y Zhang, J Wang, G Zhou, Z Zhang
"SRECT: Machine-Specific Spatial-Resolution Enhancement in Computed Tomography."
ICASSP 2024, 2024. [DOI]
E Zhang, W Chen, X Xu, Z Zhang, J Li
"Breast ultrasound computer-aided diagnosis using structure-aware triplet path networks."
ICASSP 2024, 2024. [DOI]
J Li, Y Wang, X Chen, ..., Z Zhang, et al.
"Unlocking the Potential of Early Epochs: Uncertainty-aware CT Metal Artifact Reduction."
Medical Image Analysis, 2024. [arXiv]
Z Zhang, et al.
"Reliable Deep Diffusion Tensor Estimation: Rethinking the Power of Data-Driven Optimization Routine."
arXiv, 2024. [arXiv]
2023
Y Jiang, Z Zhang, et al.
"Biology-guided deep learning predicts prognosis and cancer immunotherapy response."
Nature Communications, 2023. [DOI]
C Chen, J Wang, J Pan, C Bian, Z Zhang, et al.
"GraphSKT: Graph-Guided Structured Knowledge Transfer for Domain Adaptive Lesion Detection."
IEEE Transactions on Medical Imaging, 2023. [DOI]
W Ji, J Li, C Bian, Z Zhang, L Cheng
"SemanticRT: A Large-Scale Dataset and Method for Robust Semantic Segmentation in Multispectral Images."
ACM MM 2023, 2023. [DOI]
L Li, Y Tang, Y Zhang, Z Li, G Zhou, H Zhou, Z Zhang
"Federated Multi-organ Dynamic Attention Segmentation Network with Small CT Dataset."
CMMI-CAIP Workshop, 2023. [DOI]
X Shi, Y Zhang, L Li, Y Tang, Z Li, Z Zhang
"Label-Efficient Cross-Resolution Polyp Segmentation in Colonoscopy."
CMMI-CAIP Workshop, 2023. [DOI]
HY Zhou, Y Fu, Z Zhang, et al.
"Protein Representation Learning via Knowledge Enhanced Primary Structure Reasoning."
bioRxiv, 2023. [DOI]
Z Zhang, et al.
"Metal Artifact Reduction."
Medical Image Synthesis: Methods and Clinical Applications, 2023. [DOI]
2022
Y Jiang, Z Zhang, Q Yuan, W Wang, H Wang, T Li, W Huang, J Xie, ...
"Predicting peritoneal recurrence and disease-free survival from CT images in gastric cancer using multi-task deep learning."
The Lancet Digital Health, 2022. [DOI]
Z Yang, J Pan, Y Yang, X Shi, HY Zhou, Z Zhang, C Bian
"ProCo: Prototype-Aware Contrastive Learning for Long-Tailed Medical Image Classification."
MICCAI 2022, 2022. [DOI]
S Diao, Y Tian, W Hu, J Hou, R Lambo, Z Zhang, Y Xie, X Nie, F Zhang, ...
"Weakly Supervised Framework for Cancer Region Detection of Hepatocellular Carcinoma in Whole-Slide Pathologic Images."
The American Journal of Pathology, 2022. [DOI]
Y Yan, X Wu, C Li, Y He, Z Zhang, et al.
"Topological EEG Nonlinear Dynamics Analysis for Emotion Recognition."
IEEE Transactions on Cognitive and Developmental Systems, 2022. [DOI]
Z Zhang, et al.
"Human-level comparable control volume mapping with a deep unsupervised-learning model for image-guided radiation therapy."
Computers in Biology and Medicine, 2022. [DOI]
Z Zhang, et al.
"Automatic quantification of retinal photoreceptor integrity to predict persistent disease activity in neovascular age-related macular degeneration using deep learning."
Frontiers in Neuroscience, 2022. [DOI]
2021
Z Zhang, L Yu, X Liang, W Zhao, L Xing
"TransCT: Dual-Path Transformer for Low Dose Computed Tomography." [GitHub]
MICCAI 2021, 2021. [DOI]
X Liang, N Li, Z Zhang, J Xiong, S Zhou, Y Xie
"Incorporating the hybrid deformable model for improving the performance of abdominal CT segmentation."
Medical Image Analysis, 2021. [DOI]
Z Zhang, X Liang, W Zhao, L Xing
"Self-supervised CT super-resolution with hybrid model."
Computers in Biology and Medicine, 2021. [DOI]
Z Zhang, X Liang, W Zhao, L Xing
"Noise2Context: Context-assisted learning 3D thin-layer for low-dose CT."
Medical Physics, 2021. [DOI]
L Yu, Z Zhang, X Li, H Ren, W Zhao, L Xing
"Metal artifact reduction in 2D CT images with self-supervised cross-domain learning."
Physics in Medicine and Biology, 2021. [DOI]
Z Zhang, L Yu, W Zhao, L Xing
"Modularized data-driven reconstruction framework for nonideal focal spot effect elimination in computed tomography."
Medical Physics, 2021. [DOI]
Z Zhang, et al.
"ComputeCOVID19+: Accelerating COVID-19 Diagnosis and Monitoring via High-Performance Deep Learning on CT Images."
ACM ICMIP, 2021. [DOI]
Z Zhang, et al.
"Real-Time Precise Human-Computer Interaction System Based on Gaze Estimation and Tracking."
Wireless Communications and Mobile Computing, 2021. [DOI]
N Li, S Zhou, G Zhao, Z Zhang, Y Xie, X Liang
"Iterative stripe artifact correction framework for TOF-MRA."
Computers in Biology and Medicine, 2021. [DOI]
W Zhao, L Shen, MT Islam, W Qin, Z Zhang, X Liang, G Zhang, S Xu, X Li
"Artificial intelligence in image-guided radiotherapy: a review of treatment target localization."
Quantitative Imaging in Medicine and Surgery, 2021. [DOI]
2020
L Yu, Z Zhang, X Li, L Xing
"Deep Sinogram Completion with Image Prior for Metal Artifact Reduction in CT Images."
IEEE Transactions on Medical Imaging, 2020. [DOI]
Z Zhang, X Liang, W Qin, S Yu, Y Xie
"matFR: a matlab toolbox for feature ranking." [GitHub]
Bioinformatics, 2020. [DOI]
2019
X Liang, N Li, Z Zhang, S Yu, W Qin, Y Li, S Chen, H Zhang, Y Xie
"Shading correction for volumetric CT using deep convolutional neural network and adaptive filter."
Quantitative Imaging in Medicine and Surgery, 2019. [DOI]
X Liang, Y Jiang, W Zhao, Z Zhang, C Luo, J Xiong, S Yu, X Yang, J Sun, Q Zhou, T Niu, Y Xie
"Scatter correction for a clinical cone-beam CT system using an optimized stationary beam blocker in a single scan."
Medical Physics, 2019. [DOI]
X Liang, N Li, Z Zhang, S Yu, Y Li, S Chen, H Zhang, Y Xie
"A Technical Review of Convolutional Neural Network-Based Mammographic Breast Cancer Diagnosis."
Computational and Mathematical Methods in Medicine, 2019. [DOI]
J Yang, Z Zhang, Y Zhu, Y Xie
"An accurate estimation of T2* mapping for fast magnetic resonance imaging."
ACM SIGGRAPH, 2019. [DOI]
Z Zhang, et al.
"A Matlab Toolbox for Feature Importance Ranking."
ICMIPE, 2019. [DOI]
Z Zhang, et al.
"An improved physics model for multi-material identification in photon counting CT."
Medical Imaging, 2019. [DOI]
2018
Z Zhang, X Liang, X Dong, Y Xie, G Cao
"A Sparse-View CT Reconstruction Method Based on Combination of DenseNet and Deconvolution." [GitHub]
IEEE Transactions on Medical Imaging, 2018. (ESI Highly Cited, 528+ Citations) [DOI]
Z Zhang, et al.
"Comparison of activation functions in a shallow convolutional neural network for natural image sharpness assessment."
SPIE, 2018. [DOI]
Z Zhang, G Dai, X Liang, S Yu, L Li, Y Xie
"Can Signal-to-Noise Ratio Perform as a Baseline Indicator for Medical Image Quality Assessment."
IEEE Access, 2018. [DOI]
2017
X Liang, Z Zhang, T Niu, S Yu, S Wu, Z Li, H Zhang, Y Xie
"Iterative image-domain ring artifact removal in cone-beam CT."
Physics in Medicine and Biology, 2017. [DOI]
2016
Z Zhang, S Yu, X Liang, Y Zhu, Y Xie
"A novel design of ultrafast micro-CT system based on carbon nanotube: A feasibility study in phantom."
Physica Medica, 2016. [DOI]
S Yu, S Wu, Z Zhang, et al.
"Explicit vascular reconstruction based on adjacent vector projection."
BioEngineered, 2016. [DOI]
Experience
JancsiTech, China
2022 – Present
Associate Professor | Chief Scientist
Leading AI Medical Imaging R&D Team
ELSEVIER and Stanford University's Top 2% Scientists 2025
IEEE TMI Distinguished Reviewer - Bronze Level, IEEE Transactions on Medical Imaging, 2020-2022
1st Place, 2022 VizWiz Grand Challenge (CVPR2022), 2022
ESI Highly Cited Paper, DD-Net (IEEE TMI 2018), 2020-2024
Dean's Scholarship, Chinese Academy of Sciences, 2018
Outstanding Paper Award, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, 2018
Dean's Scholarship, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, 2017
Pacemaker to Merit Student, Chinese Academy of Sciences, 2016
Merit Student, Chinese Academy of Sciences, 2016
Dean's Scholarship, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, 2016
Outstanding Graduate Student Award, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, 2016
Best Oral, AOCMP, 2015
Outstanding Graduate Student Award, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, 2015
Professional Activities
Journal Reviews:
IEEE Transactions on Medical Imaging (TMI)
IEEE Journal of Biomedical and Health Informatics (JBHI)
IEEE Access
Medical Physics (MP)
Physics in Medicine & Biology (PMB)
Quantitative Imaging in Medicine and Surgery (QIMS)
Frontier in Oncology
Nature Communications
Displays
BioMed Research International
Applied Optics
Journal of X-Ray Science and Technology
Academic Participation: Visiting Researcher, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences Distinguished Professor, The First Hospital of Jilin University | Zhejiang-Finland Joint Laboratory for Children's Health AI | Shenzhen Fourth People's Hospital Industry Mentor, Southern Medical University | Hong Kong University of Science and Technology (Guangzhou) Committee Member, Chinese Medical Equipment Association AI & Medical Robotics Branch Committee Member, Chinese Society of Biomedical Engineering - Medical Signal Physics Standing Committee Member, Zhejiang Biomedical Engineering Society - Children's Health Branch Expert, Shenzhen Science & Technology Experts | Shenzhen Science & Technology Association Expert Group Member, Zhejiang AI Expert Service Team Committee Member, Chinese Hospital Association Medical AI Professional Committee Expert Advisory, National Postdoctoral Innovation (Jiangmen) Demonstration Center
Program Committee Member: DLBIBM 2022
Guest Editor: Frontiers in Radiation